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. 2015 Dec 17;8:3827–3835. doi: 10.2147/OTT.S92314

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© 2015 Fu and Cao. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effect of miR-125a-5p downregulation on prostate cancer cell proliferation and migration.

Notes: DU145 and VCaP cells were transduced with miR-125a-5p inhibitor lentivirus, 125a-5p-inhibitor, or C-miRNA. After lentiviral transduction, qRT-PCR was used to evaluate the knockdown efficiency of lentiviral transduction in DU145 (A) and VCaP (B) cells (*P<0.05). Cancer cell proliferation in DU145 (C) and VCaP (D) cells was evaluated by MTT assay (*P<0.05). Cancer migration in DU145 (E) and VCaP (F) cells was evaluated by a transwell assay and H&E staining (*P<0.05).

Abbreviations: C-miRNA, control-microRNA; qRT-PCR, quantitative reverse transcription-polymerase chain reaction; H&E, hematoxylin and eosin.