Fig. 2.

Prophylaxis with oleuropein and lidocaine on heart rate (A), mean blood pressure (B) and rate pressure product (C) before, during and after ischemia. Drug means the infusion of oleuropein or lidocaine; Ii, initiation time of ischemia; Ie, end time of ischemia and Rep, reperfusion time. Con, control group; Lido-p, prophylaxis group with 10 mg/kg lidocaine; Ole10-p, prophylaxis group with 10 mg/kg oleuropein; Ole50-p, prophylaxis group with 50 mg/kg oleuropein. a, P<0.05; b, P<0.001; c, P<0.001 vs. control group