Table 2.
Effects of treatment with lidocaine and oleuropein on the magnitude of reperfusion arrhythmia
Arrhythmia parameters | Con | Lido-t | Ole10-t |
---|---|---|---|
Onset of arrhythmia (s) | 2.6 0.7 | 10.6 1.8* | 4.6 1.2 |
Duration of arrhythmia (s) | 172.0 41.0 | 72.0 25.0** | 15.0 98.0 |
PVB numbers | 52.0 12.0 | 17.0 4.1** | 59.0 27.0 |
VT numbers | 14.0 1.5 | 4.0 1.1** | 18.0 2.5 |
VF numbers | 3.3 1.0 | 3.0 1.2 | 4.5 1.3 |
VT duration | 29.0 4.1 | 16.0 6.0 | 16.0 4.0 |
VF duration | 86.0 30.0 | 6.5 0.5** | 12.0 3.1** |
VT (%) | 84 | 50** | 40*** |
VF (%) | 92 | 50** | 100 |
Mortality rate (%) | 25 | 20 | 50 |
PVB, premature ventricular beats; VT, ventricular tachycardia, VF, ventricular fibrillation; Con, control group; Ole10-t, treatment group with 10mg/kg oleuropein, O50-t, treatment group with 50mg/kg oleuropein, Lido-t, treatment group with 10mg/kg lidocaine.
P< 0.05;
P<0.01 and
P<0.001 vs. control group.