Table 1.
Demographic and Clinical Characteristics of the Study Population
Variables | All patients (n=110 484) | HCV Genotype 1 (n=88 348) | HCV Genotype 2 (n=13 077) | HCV Genotype 3 (n=8 337) | HCV Genotype 4 (n=1 082) | P-value |
---|---|---|---|---|---|---|
Demographics | ||||||
Age in years mean (SD) | 51.9 (6.7) | 51.9 (6.6) | 52.7 (7.5) | 50.2 (6.4) | 51.5 (6.3) | <0.0001 |
Male gender, (%) | 97.0 | 97.0 | 96.9 | 97.1 | 97.4 | 0.74 |
Race, (%) | <0.0001 | |||||
White | 52.6 | 47.5 | 71.9 | 76.2 | 44.3 | |
African American | 33.2 | 39.3 | 10.1 | 5.3 | 37.2 | |
Hispanic | 5.6 | 5.1 | 7.7 | 7.4 | 9.4 | |
Others | 1.5 | 1.5 | 1.8 | 1.7 | 1.3 | |
Missing | 7.0 | 6.6 | 8.5 | 9.1 | 7.3 | |
Period of Service, (%) | <0.0001 | |||||
World War I/II | 4.3 | 4.1 | 7.1 | 2.1 | 2.8 | |
Vietnam | 70.2 | 70.6 | 70.3 | 66.5 | 70.1 | |
Post-Vietnam | 25.5 | 25.3 | 22.6 | 31.4 | 27.2 | |
Clinical, (%) | ||||||
Yes of HCV diagnosis | ||||||
2000–2002 | 36.0 | 36.2 | 35.4 | 35.5 | 34.9 | 0.04 |
2003–2005 | 38.5 | 38.3 | 39.5 | 38.1 | 37.9 | |
2005–2009 | 25.5 | 25.4 | 25.1 | 26.3 | 27.2 | |
Diabetes | 11.1 | 11.7 | 9.3 | 7.3 | 13.5 | <0.0001 |
Alcohol use | 51.2 | 51.7 | 46.4 | 53.1 | 52.4 | <0.0001 |
HIV coinfection | 4.3 | 4.6 | 2.5 | 2.9 | 5.7 | <0.0001 |
Body mass index | ||||||
<18.5 | 1.3 | 1.3 | 0.9 | 1.3 | 0.9 | <0.0001 |
18.5–24.9 | 31.9 | 32.1 | 29.4 | 33.7 | 28.3 | |
25.0–29.9 | 39.4 | 39.6 | 38.4 | 38.7 | 43.5 | |
>30 or higher | 28.3 | 27.9 | 31.7 | 27.2 | 27.9 | |
Antiviral treatment | ||||||
No treatment | 78.5 | 80.4 | 70.8 | 70.6 | 80.4 | <0.0001 |
Sustained response | 6.9 | 4.9 | 16.4 | 14.0 | 4.7 | |
No response | 7.9 | 8.3 | 5.4 | 7.8 | 8.3 | |
Undeterminable | 6.6 | 6.4 | 7.4 | 7.6 | 6.6 |