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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Neurobiol Dis. 2015 Mar 6;77:173–190. doi: 10.1016/j.nbd.2015.02.022

Figure 8. Decreased surface binding of BDNF in Ts65Dn synaptosomes.

Figure 8

2N (A and B) and Ts65Dn (C and D) cortical synaptosomes were incubated with QD-BDNF (A and C) or QD alone (QD-veh, B and D). Yellow arrows indicate QD visualized on the surface of synaptosomes by confocal microscopy. Bar = 100µm. (E) The number of QD, normalized to the total number of actin positive synaptosomes, was quantified in each condition. n = 6 preps per genotype, ** p<0.005 versus 2N.