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. 2016 Jan;57(1):46–55. doi: 10.1194/jlr.M057943

TABLE 1.

Comparison of the lipid measures reported in (22) and model simulations of the LMK model

RVX-208 (150 mg Dose)
Reported Data Model Simulation
Upregulation of ApoA-I synthesis (%) NA 6.8
Change in HDL-C (%) 8.3 (−1.9 to 17.9) 8.3 (7.6–9.1)
Change in ApoA-I (%) 5.6 (−1.1 to 14.3) 5.9 (5.4–6.6)
Change in HDL particle concentration (%) 5.1 (−4.8 to 16.5) 4.8 (4.3–5.2)
Change in HDL particle size (%) 1.1 (−1.1 to 2.4) 0.7 (0.6–0.7)
Change in LDL-C (%) 1.0 (−14.2 to 10.1) 8.4 (7.8–9.3)
Change in RCT rate (%) 8.5 (7.9–9.4)

Clinical data are given with their median and interquartile range; simulation results are given with mean and 95% CI of mean .