Fig. 2.
Hematopoietic ABCA1 deletion worsened insulin resistance. BMT-WT and BMT-ABCA1−/− mice were fed the HFHSC diet for 22 weeks. Plasma fasting glucose (A) and plasma fasting insulin (B) were measured at week 21. C: Calculated HOMR-IR. D: Intraperitoneal glucose tolerance test. E: Intraperitoneal insulin tolerance test. F: Area under the curve (AUC) was calculated to measure the degree of the glucose tolerance impairment. G: AUC was calculated to measure the degree of the insulin tolerance impairment. *P < 0.05 versus BMT-WT mice; n = 10–15 per group.