Table 2. Drug hyper-susceptibility of the had mutants.
Drug (μg/ml) | wt/pGBT | ΔhadC/pGBT | ΔhadC/pC | ΔhadABC/pABC | ΔhadABC/pBC | ΔhadABC/pB |
---|---|---|---|---|---|---|
Ethambutol (5) | 1 | 1 | 1 | 1 | 1 | 1 |
Isoniazid (5) | 1 | 10 −2 | 1 | 1 | 1 | 10 −2 |
Ethionamid (10) | 1 | 10 −2 | 1 | 1 | 1 | 10 −2 |
Rifampicin (2) | 1 | < 10 −3 | 1 | 1 | 1 | < 10 −3 |
Vancomycin (1) | 1 | 10 −2 | 1 | 1 | 1 | 10 −4 |