Fig 2. Enhanced GFAP protein expression in the hippocampus of MK-801-treated rats as measured by western blotting.

MK-801 was administered by intraperitoneal injection (0.5 mg/10ml/kg body weight) daily for 6 days. Control animals received equal volumes of normal saline. GFAP expression was detected by western blotting of hippocampal lysates from MK-801-treated (MK801) and Control (Ctrl) rats (n = 4 per group). Densitometric values expressed as mean ± S.E.M relative to the gel loading control. Statistical differences between two groups were determined by student's t-tests. **P<0.01 vs. control group.