N
|
total # of genes |
T
|
set of transcripts; T
ik is the k
th transcript of the i
th gene; T
i denotes the transcripts of the i
th gene |
l
ik
|
length of transcript T
ik
|
r
|
set of reads; r
ij is the j
th read aligned to the i
th gene; r
i is the read set aligned to the i
th gene |
p
ik
|
the probability of a read generated by transcript T
ik in the i
th gene |
P
i
|
the probability of a read generated by transcript T
i in the i
th gene, specifically, [p
i1, …, p
i,|Ti|] |
P
|
concatenate of all P
i, specifically, [P
1,P
2, …,P
N] |
ρ
ik
|
relative abundance of the transcript T
ik in the i
th gene |
π
|
transcript expression; π
ik is the expression of the k
th transcript of the i
th gene |
ϕ
ik
|
average expressions (normalized) of transcript T
ik’s neighbors in the transcript network |
α
|
parameters of Dirichlet distribution; α
ik = λϕ
ik + 1 is the parameter of the Dirichlet distribution of p
ik
|
q
ijk
|
read sampling probability, if read r
ij is aligned to transcript T
ik, otherwise q
ijk = 0 |
S
|
binary matrix for transcript interaction network |