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. 2015 Dec 23;10(12):e0145441. doi: 10.1371/journal.pone.0145441

Table 1. Neuroscale scoring protocol (adapted from Korenova et al., 2009).

General observation (normal 0; maximum 4 points) 4
1 Abnormal posture
1 Forelimb paralysis
1 Hind-limb paralysis
1 Vocalization during examination
Hind-limb extension reflex (normal 0; maximum 3 points) 3
0 Hind-limb extended with spreading toes
1 Hind-limb extended with spreading toes, distance between limbs is shorter than in previous scoring
2 Hind-limb almost in contact, toes spread (or flexed)
3 Hind-limb extended clasped or crossed with toes flexed
Beam walking test—escape latency– 3 testing conditions (normal 0–5; maximum 15 points) 15
0 Latency ≤2s
1 Latency 2.1–4.0s
2 Latency 4.1–6.0s
3 Latency 6.1–10.0s
4 Latency 10.1s and more
5 Animal not able to perform the task
Beam walking test—Number of hind-limb slips– 3 testing conditions (normal 0–5; maximum 15 points) 15
0 Hind-limb slips ≤1
1 Hind-limb slips 1.1–2.0
2 Hind-limb slips 2.1–3.0
3 Hind-limb slips 3.1–5.0
4 Hind-limb slips5.1–8.0
5 More than 8 hind-limb slips; animal is not able to perform the task
Prehensile traction-test—latency to fall (normal 0; maximum 5 points) 5
5 Latency ≤2s
4 Latency 2.1–4.0s
3 Latency 4.1–6.0s
2 Latency 6.1–10.0s
1 Latency 10.1–15.0s
0 More than 15s
Maximum points 42