Fig 7. Nef-GPG motif is required for Nef-enhanced infectivity of HIV-1.

Relative infectivity of HIV-1expressing Nef-GPG mutations produced in Jurkat (A) or 293T (B) cells. Infectivity was analysed 48h post-infection by Luciferase assays in TZM-bl reporter cells. Results are expressed as the percentage of infectivity relative to that of the wild type viruses normalized to 100%. Values are the mean ± SD of three independent infections, each measured in duplicate. ***, p< 0.001.