TABLE 2.
Treatment of adolescent acne vulgaris with clindamycin (clin)-BP 3.75% aqueous gel. Comparison with vehicle, intention-to-treat population population
| ADOLESCENT ACNE (≤12 TO <18 YEARS) (N=289) | |||
|---|---|---|---|
| Clin-BP 3.75% gel (N=155) | Vehicle (N=134) | P-value | |
| Mean age (years) | 14.8 | 15.1 | 0.101 |
| Gender (male/female, %) | 61.3%/38.7% | 59.0%/41.0% | 0.592 |
| Baseline severity (moderate/severe, %) | 85.2%/14.8% | 85.5%/14.2% | 0.805 |
| LESION REDUCTION AT WEEK 12 | |||
| Mean percent reduction in Inflammatory lesions | 59.9% | 22.6% | <0.001 |
| Mean percent reduction in noninflammatory lesions | 50.5% | 21.3% | <0.001 |
| TREATMENT SUCCESS AT WEEK 12 | |||
| Subjects with ≥2 grade reduction in EGSS | 33.1% | 8.5% | <0.001 |
| Subjects clear/almost clear (subject self-assessment) | 34.7% | 12.8% | <0.001 |