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. 2015 Dec 23;10(12):e0144836. doi: 10.1371/journal.pone.0144836

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© 2015 Sakashita et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 6 — (A) Bi-dimensional PCA of E13.5 female and male single-PGC gene expression patterns. The first principal component (PC1) captures 4.93% of the gene expression variability and the second principal component (PC2) captures 4.25%. The red and blue spheres represent single female (n = 67) and male (n = 77) PGCs, respectively. (B) Hierarchical clustering analysis of transcriptome data sets (FSG: 651, MSG: 428) of female and male single PGCs. (C) Heat map of the relative expression of apoptotic process-related genes (n = 15). (D) Heat map of the relative expression of meiotic and mitotic cell cycle-related genes (n = 26). (E) Relation between apoptosis and meiotic and mitotic cell cycle in female PGCs. The numbers indicate the number of PGCs.