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. 2015 Dec 23;10(12):e0145303. doi: 10.1371/journal.pone.0145303

Table 5. Healthcare utilisation in the first three years of life. Daily vitamin D versus control.

n Control* n Daily* Mean difference (95% CI) p n Adjusted** mean difference (95% CI) p
Total cost 31 1176.14 (437.03, 3165.29) 36 1187.97 (441.42, 3197.10) 1.02 (-1.60, 1.65) 0.95 53 1.07 (-1.62, 1.86) 0.81
All Visits 31 1130.03 (419.90, 3041.18) 36 1118.79 (407.48, 3071.74) -1.01 (-1.65, 1.60) 0.95 53 1.02 (-1.70, 1.79) 0.93
Prescription cost 31 25.28 (4.06, 157.60) 36 35.52 (11.59, 108.85) 1.40 (-1.49, 2.94) 0.36 53 1.65 (-1.43, 3.90) 0.25
Year 1 cost 31 287.15 (38.09, 2164.62) 36 383.75 (86.49, 1702.75) 1.34 (-1.75, 3.16) 0.50 53 1.67 (-1.58, 4.39) 0.30
Year 2 cost 31 247 (103, 607) 36 248 (123, 487) - 0.92 - - -
Year 3 cost 31 239 (103, 552) 36 212 (96, 463) - 0.57 - - -
Primary care cost 31 387.61 (145.47, 1032.77) 36 450.39 (242.26, 837.15) 1.15 (-1.28, 1.72) 0.47 53 1.34 (-1.16, 2.05) 0.20
Secondary care cost 31 632 (206, 1853) 36 368 (155, 1502) - 0.42 - - -
Wheeze cost 31 0 (0, 0) 36 0 (0, 0) - 0.71 - - -
Cough cost 31 0 (0, 36) 36 0 (0, 36) - 0.26 - - -
URTI cost 31 180 (36, 324) 36 150 (54, 234) - 0.78 - - -
LRTI cost 31 0 (0, 0) 36 0 (0, 0) - 0.75 - - -
Bronchiolitis cost 31 0 (0, 0) 36 0 (0, 0) - 0.89 - - -
Overall resp cost 31 170.72 (27.39, 1064.22) 36 141.17 (27.11, 735.10) -1.21 (-3.16, 2.14) 0.69 - - -
Food allergy cost 31 0 (0, 0) 36 0 (0, 0) - 0.35 - - -
Eczema cost 31 0 (0, 88) 36 0 (0, 36) - 0.62 - - -

URTI (Upper respiratory tract infection), LRTI (Lower respiratory tract infection).

All costs are in pounds sterling.

*Mean ± 95% CI or Median (IQR)

**Adjusted for mother’s age, mother’s age on leaving education and gestational age as potential covariates, and ethnicity (Caucasian, Asian, Middle Eastern, Black), parity, BMI>30, smoking during pregnancy, mode of delivery (vaginal, instrumental or caesarean) as potential cofactors.

Analysis performed on Ln data, results have undergone exponentiation for presentation in tables.