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. 2015 Dec 15;11(12):e1005706. doi: 10.1371/journal.pgen.1005706

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© 2015 Deng et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5 — (A) The cumulative percentage of differentially expressed genes representing proteins with or without ribosomal pausing in trm9Δ cells. Based on ribosome footprinting data from elp3Δ cells lacking mcm⁵U and mcm⁵s²U [24] (B) Percentages of significantly down-regulated (blue), up-regulated (red) and unchanged (grey) proteins from transcripts with or without ribosomal pausing. (C) The cumulative percentage of genes with a given AGA and GAA codon usage, in groups of proteins with or without ribosomal pausing in trm9Δ cells. (D) Percentages of proteins enriched with AGA and GAA codons (red) and other proteins (grey) in genes with pausing or without ribosome pausing. (E) The cumulative percentage of genes with a given frequency of AGA and GAA codon runs, in groups of proteins with or without ribosomal pausing in trm9Δ cells. (F) Boxplot of the number of codon runs identified in groups of proteins with and without ribosomal pausing. (G) Similar to (E), but only proteins enriched with AGA and GAA codons in both groups were considered. (H) Similar to (F), but only proteins enriched with AGA and GAA codons in both groups were considered.