Table 2. Proportional hazards regressions predicting mortality from Log sIgA secretion rate, with and without adjustment for covariates.

		Model
		1			2			3			4			5
Cause of Death	Deaths	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p
All Causes	300	0.81	0.73 to 0.91	< .001	0.85	0.76 to 0.95	.004	0.85	0.75 to 0.95	.004	0.86	0.76 to 0.96	.008	0.86	0.76 to 0.96	.008
Cardiovascular Disease	96	0.83	0.68 to 1.02	.070	0.86	0.71 to 1.06	.152	0.87	0.71 to 1.06	.167	0.89	0.72 to 1.09	.247	0.89	0.72 to 1.09	.247
Respiratory Disease	46	0.83	0.62 to 1.10	.197	0.88	0.66 to 1.17	.387	0.89	0.67 to 1.20	.454	0.92	0.69 to 1.22	.556	0.90	0.68 to 1.21	.495
Cancer	98	0.72	0.59 to 0.87	< .001	0.74	0.61 to 0.90	.002	0.74	0.61 to 0.90	.002	0.74	0.61 to 0.89	.002	0.74	0.61 to 0.90	.002
Lung Cancer	29	0.83	0.57 to 1.19	.301	0.93	0.65 to 1.32	.674	0.94	0.66 to 1.35	.752	0.93	0.65 to 1.33	.689	0.93	0.65 to 1.33	.689
Other Cancer	69	0.68	0.54 to 0.85	< .001	0.68	0.54 to 0.85	< .001	0.68	0.54 to 0.85	< .001	0.68	0.54 to 0.85	< .001	0.68	0.54 to 0.85	< .001
Other causes	60	0.98	0.75 to 1.28	.868	1.01	0.77 to 1.32	.956	1.01	0.77 to 1.32	.958	1.01	0.78 to 1.32	.922	1.01	0.78 to 1.32	0.917

Model1: adjusted for assay batch and sex. Model2: model1 + smoking status. Model3: model2 + Medications. Model4: model3 + Self-rated Health. Model5: model4 + manual social class.

Hazard ratios are per standard deviation of log sIgA secretion rate.