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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Nov 7;89(0 0):177–184. doi: 10.1016/j.yjmcc.2015.11.009

Fig 6. ROS production in mdx mice is RyR2-dependent.

Fig 6

(A) DCF fluorescence time course showing increased ROS production in mdx mice, which is reduced by Nox2 inhibitor gp91ds-tat and RyR2-inhibitor JTV519 (JTV) and enhanced by RyR2 activator caffeine. (B) Quantification of normalized DCF slope in ventricular myocytes from WT mice, mdx mice, mdx with JTV, mdx with caffeine cardiomyocytes and mdx with gp91ds-tat. *P<0.05 vs. WT. #P<0.05 vs. mdx.