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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Oct 13;89(0 0):87–97. doi: 10.1016/j.yjmcc.2015.10.011

Figure 1.

Figure 1

TLR ligands increase the expression of miR-130a and MI-induced decreases in the levels of miR-130a in the myocardium. (A and B) Mice were treated with and without Pam3CSK or CpG-ODN immediately after permanent ligation of LAD coronary artery. Sham control mice were also treated with and without Pam3CSK4 or CpG-ODN. Twenty-four hours after LAD ligation, hearts were harvested for microRNA measurement. (C) MI decreased expression of miR-130a in the myocardium. Three days after MI, hearts were harvested for microRNA measurement. N=3 in sham group. N=4 in MI group. *p<0.05 compared with indicated group.