Table 6.

Correlations between regional atrophy and neurocognitive and language measures

MRI volume (median [IQR])
	L hippocampus	L lateral temporal	L inferior parietal
	0.26 (0.23 – 0.27)	1.83 (1.65 – 1.96)	0.77 (0.69 – 0.84)
Correlation (ρ value [p value])
	L hippocampus	L lateral temporal	L inferior parietal
MOCA	0.11 (0.47)	0.46** (0.002)	0.60** (<0.0001)
FAB	0.18 (0.24)	0.45** (0.002)	0.52** (0.0001)
FBI	0.22 (0.15)	0.08 (0.59)	−0.06 (0.68)
CDR-SB	−0.11 (0.47)	−0.26 (0.09)	−0.38 (0.03)
AVLT trial 1	−0.17 (0.28)	0.01 (0.95)	0.04 (0.79)
AVLT LT % retention	0.24 (0.13)	0.38* (0.01)	0.38* (0.01)
DKEFS sorting	−0.09 (0.57)	0.13 (0.44)	0.26 (0.11)
VOSP cube	0.24 (0.12)	0.42* (0.01)	0.37* (0.01)
WAB AQ	0.19 (0.23)	0.44** (0.003)	0.45** (0.002)
WAB repetition	−0.12 (0.43)	0.26 (0.09)	0.33 (0.03)
Token test	0.13 (0.41)	0.44** (0.003)	0.47** (0.001)
BNT	0.23 (0.13)	0.29 (0.05)	0.26 (0.08)

^*Trend for significance (p ≤ 0.01)

^**Statistically significant (p < 0.004)

Abbreviations: L = left; R = right; MOCA = the Montreal Cognitive Assessment; FAB = the Frontal Assessment Battery; FBI = the Frontal Behavior Inventory; CDR-SB = Clinical Dementia Rating Sum of Boxes; AVLT = Auditory Verbal Learning Test; MOANS = Mayo Clinic’s Older Americans Normative Studies; LT = long term delayed recall; DKEFS = Delis-Kaplan Executive Function System; VOSP = the Visual Object and Space Perception Battery; WAB = Western Aphasia Battery; AQ = aphasia quotient; BNT = the Boston Naming Test