TABLE 2.
Distributions of normalized EBV-specific read counts by whole genome (WGS), exome, mRNA and miRNA sequencing in gastric cancers with (N=23) and without (N=272) EBER-ISH confirmation of EBV status
| EBV status | WGS | Exome | mRNA | miRNA | ||||
|---|---|---|---|---|---|---|---|---|
| cases | #reads | cases | #reads | cases | #reads | cases | #reads | |
| EBER-ISH-positive* | 4 | 36,000–170,000 | 13 | 280–17,000 | 13 | 5–180 | 13 | 6000–1,500,000 |
| presumptive positive | 3 | 25,000–68,000 | 13 | 210–7400 | 11 | 25–290 | 11 | 140,000–1,100,000 |
| EBER-ISH-negative | 0 | - | 7 | 0–1 | 9 | 0–1 | 9 | 1–580 |
| presumptive negative | 70 | 0–193 | 230 | 0–93 | 204 | 0–1 | 260 | 0–2200 |
*
omits one case with 0 mRNA reads and 60 miRNA reads (see Results for details)