Table 1. Comparison of clinicopathologic and perioperative data of patients undergoing laparoscopic liver resection for posterosuperior (PS) and anterolateral lesions (AL).
| Variables | Whole study population, n (%) | PS (n=70; 35.5%), n (%) | AL (n=127; 64.5%), n (%) | P* |
|---|---|---|---|---|
| Demographics | ||||
| Females | 74 (37.6) | 20 (28.6) | 54 (42.5) | 0.05 |
| Age, years (SD) | 60.0 (±11.3) | 60.1 (±11.3) | 59.9 (±11.2) | 0.91 |
| Median ASA | 2 | 2 | 2 | 0.50 |
| Histopathology | ||||
| Hepatocellular | 105 (53.3) | 37 (52.9) | 68 (53.5) | 0.28 |
| Colorectal liver metastasis | 31 (15.7) | 15 (21.4) | 16 (12.6) | |
| Other malignancies | 19 (9.6) | 7 (10.0) | 12 (9.4) | |
| Benign | 42 (21.3) | 11 (15.7) | 31 (24.4) | |
| Perioperative variables | ||||
| Operative time, min (SD) | 230 (±124.4) | 274 (±128.1) | 206 (±116.0) | <0.001 |
| EBL, mL (SD) | 449 (±664.6) | 502 (±701.0) | 418 (±641.9) | 0.40 |
| Blood transfusion, patients (SD) | 32 (±16.2) | 11 (±15.7) | 21 (±21.3) | 0.88 |
| Conversion to open | 30 (15.2) | 16 (22.9) | 14 (11.0) | 0.03 |
| Additional organ resectionβ | 15 (7.6) | 4 (5.7) | 11 (8.7) | 0.46 |
| Previous abdominal surgery | 56 (28.4) | 23 (32.9) | 33 (26.0) | 0.31 |
| Pathology | ||||
| Liver cirrhosis (all Child-Pugh A) | 51 (25.9) | 20 (28.6) | 31 (24.4) | 0.52 |
| Tumor size, mm (SD) | 31.5 (±21.8) | 34.0 (±23.9) | 30.2 (±20.5) | 0.24 |
| Median no. of tumors [range] | 1 [1-4] | 1 [1-3] | 1 [1-4] | 0.36 |
| Surgical margin, mm (SD) | 9.3 (±10.4) | 6.9 (±8.9) | 10.7 (±10.9) | 0.01 |
| R0 resection | 189 (95.9) | 68 (97.1) | 121 (95.3) | 0.53 |
| Morbidity and mortality | ||||
| 90-day morbidity | 42 (21.3) | 16 (22.9) | 26 (20.5) | 0.70 |
| 90-day mortality | 1 (0.5) | 0 (0.0) | 1 (0.8) | 0.46 |
| Major complications (grade 3-5) | 11 (5.6) | 5 (7.1) | 6 (4.7) | 0.48 |
| LOS, days, mean (SD) | 4.8 (±3.6) | 4.8 (±2.6) | 4.8 (±4.1) | 0.92 |
*, analysis is comparing the PS and AL cohorts only; β, excludes gallbladder as an addition organ as cholecystectomy is considered as part of the liver resection; α, cirrhosis is based on pathology of resected specimen. SD, standard deviation; ASA, American Society of Anesthesiologists; EBL, estimated blood loss; LOS, length of stay.