Levels of mediators that signficantly changed after ESI treatment by diagnosis. In DH cohort (top row), levels of IL-17 and VEGF were significantly lower in post- versus pre-treatment. In Other Dx cohort (bottom row), levels of IL-2Rα, IL-3, and SCGF-β were significantly lower in post- versus pre-treatment (*p < 0.05). Plot line represents the median, plot box represents the 25–75 % percentiles, and error bars represent the range