Table 2.

Screening recommendations in BRCA mutation carriers

	Age	Evidence and recommendation
Women
Breast self awareness	Starting at age 18 years	IIA
Clinical breast exam every 6–12 months	Starting at age 25 years	IIA
Annual breast MRI	25–70 years	IIA
Annual mammogram	30–35 to 75 years	IIA
Transvaginal ultrasound and Ca 12.5 every 6–12 months	30 years	IIC
Men
Breast self awareness	Starting at age 35 years	IIIC
Annual clinical breast exam	Starting at age 35 years	IIIC
Basal mammogram	40 years (individualised)	IIIC
Annual Prostate Cancer screening	Starting at age 40 years	IIIB
Men and women
Pancreatic and melanoma	Consider individualised screening based on cancers in the family	IIIC
Colorectal cancer screening, especially in BRCA1	Starting at 40 years or younger if family history	IIB