Table 2.

Multivariate analysis for independent factors affecting increased mucositis grade during chemotherapy

Factor		Number of patients	Odds ratio (95 % CI)	P value	Odds ratio (95 % CI)	P value
Gln	With	20	4.1 (0.6–33.7)	0.17	4.0 (0.7–29.6)	0.15
	Without	10
Gln plus ED	With	20	0.1 (0.0–0.7)	0.03*	0.1 (0.0–0.6)	0.02*
	Without	10
Age, years	<70	16	3.1 (0.7–16.5)	0.16	3.1 (0.7–16.1)	0.15
	≥70	14
Sex	Male	26	0.9 (0.1–7.7)	0.95	–	–
	Female	4
Cancer stage	IVa,b	13	14.6 (1.9–150.0)	0.01*	13.3 (1.9 –123.2)	0.01*
	II–III	17
Treatment	First line	7	0.2 (0.0–2.1)	0.19	0.2 (0.0–1.6)	0.13
	NAC	23
BMI	<21	13	1.9 (0.4–9.6)	0.44	–	–
	≥21	17

BMI body mass index, ED elemental diet, Gln glutamine, NAC neoadjuvant chemotherapy

*p < 0.05