Table 4.
Brain activation during RUN3 in the NFB and CTL groups∗.
| Anatomical region | Hemisphere | Cluster size (mm3) | MNI coordinates |
Z-score | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| (A) NFB group | ||||||
| SMA | R/L | 12654 | 1 | 4 | 55 | 5.96 |
| Basal Ganglia/Thalamus | R/L | 27417 | -26 | 4 | 0 | 4.95 |
| Cerebellum (lobule VI) | R | 5624 | 23 | -63 | -25 | 4.82 |
| IPC | R | 11389 | 38 | -48 | 45 | 4.72 |
| PMC (BA44/6) | L | 6538 | -56 | 4 | 10 | 4.61 |
| PMC(BA44/6) | R | 22918 | 53 | 4 | 45 | 4.56 |
| MFG | R | 2390 | 38 | 42 | 20 | 4.07 |
| IPC | L | 3445 | -63 | -41 | 35 | 3.90 |
| PMC (BA6) | L | 4218 | -44 | -7 | 45 | 3.59 |
| IPC/BA2 | L | 2882 | -40 | -44 | 50 | 3.56 |
| Left MTG | L | 352 | -48 | -56 | 0 | 3.07 |
| (B) CTL group | ||||||
| SMA | R/L | 3867 | -7 | -3 | 55 | 4.68 |
| Cerebellum (lobule VI) | R | 1547 | 27 | -60 | -30 | 4.32 |
| PMC (BA6) | L | 4148 | -26 | -11 | 55 | 4.24 |
| PMC (BA6/44) | L | 1547 | -56 | 4 | 35 | 4.15 |
| Basal Ganglia/Thalamus | R/L | 3585 | -26 | 0 | -5 | 3.86 |
| Precuneus/WM | R | 2109 | 16 | -37 | 15 | 3.80 |
| Precuneus/WM | L | 773 | -29 | -56 | 5 | 3.39 |
| IPC/Operculum | L | 703 | -59 | -30 | 20 | 3.31 |
| IPC | L | 844 | -37 | -41 | 50 | 3.27 |
| Basal Ganglia | R | 562 | 23 | 4 | 5 | 2.95 |
∗Values represent MNI coordinates for significant activation maxima of clusters in the one sample t-test random effects analyses (p < 0.005, uncorrected with a minimum cluster size of k = 5). BA, Brodmann area; PMC, premotor cortex; IPC, inferior parietal cortex; MFG, middle frontal gyrus; MTG, middle temporal gyrus; WM, white matter.