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. 2015 Dec 24;9:357. doi: 10.3389/fnbeh.2015.00357

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Copyright © 2015 van der Veen, Kentrop, van der Tas, Loi, van IJzendoorn, Bakermans-Kranenburg and Joëls.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of complex housing and early life MD on (A) habituation to the 5-choice SRTT chambers as expressed by the number of nose hole entries in blocks of 5 min and (B) speed of learning the 5-choice SRTT as expressed by the number of omissions at the start of each change (decrease) in stimulus duration. Note that at end of training (at stim duration 1.2 s) no group differences exist. Graphs represent mean ± SEM. Standard housing no-MD (n = 8) and MD (n = 8), complex housing no-MD (n = 16) and MD (n = 16).