Table 1.
The effect of Trigonella foenum-graecum (fenugreek) seed extract on biochemical parameters of renal and liver function tests in an acute toxicity study in animals
| Biochemical analysis | Control group (vehicle, distilled water) | Treated group (8 g/kg of fenugreek extract) | Normal range |
|---|---|---|---|
| Renal function | |||
| Sodium (mmol/L) | 138.71±0.67 | 139.12±0.73 | 139.01±0.39 |
| Potassium (mmol/L) | 6.41±0.25 | 5.84±0.29 | 6.25±0.57 |
| Urea (mmol/L) | 6.28±0.44 | 5.98±0.61 | 6.10±0.48 |
| Creatinine (mmol/L) | 52.11±2.94 | 50.98±3.13 | 51.78±4.11 |
| Liver function | |||
| lbumin (g/L) | 12.15±0.53 | 12.16±0.59 | 11.92±1.87 |
| TB (µmol/L) | 2.02±0.17 | 1.97±0.28 | 2.06±1.13 |
| CB (µmol/L) | 1.06±0.21 | 1.11±0.24 | 1.15±0.82 |
| AP (IU/L) | 135.6±9.18 | 136.8±10.11 | 135.2±13.83 |
| Globulin (g/L) | 60.22±2.7 | 59.89±3.15 | 59.28±5.85 |
| ALT (IU/L) | 52.88±4.67 | 51.98±5.37 | 53.26±6.19 |
| AST (IU/L) | 153.7±5.93 | 154.2±8.44 | 152.9±3.86 |
| GGT (IU/L) | 5.03±1.12 | 5.27±1.16 | 5.05±2.01 |
| Total protein (g/L) | 75.64±3.94 | 73.62±4.32 | 74.92±6.11 |
TB: total bilirubin; CB: conjugated bilirubin; AP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: G-glutamyl transferase. Values are expressed as mean±S.E.M. There are no significant differences among groups. Significant value at p<0.05.