Figure 4.
ST analysis reveals the internal fiber architecture of Probst bundles in subjects with ACC. Histology-based tractography of subject 4 at GW23 (A) and subject 7 at GW29 (F) depicts streamlines projecting from the intermediate zone into the Probst bundle. (B,G) ST analysis of Probst bundles reveals their internal structure as a complex arrangement of both longitudinal (C,H) and anterior-posteriorly oriented perpendicularly (D,I) cut fibers. (E,J) Corresponding to the histological ST findings, in utero tractography of subject 4 at GW22 and subject 7 at GW28 visualized not only anterior-posteriorly oriented fibers within the Probst bundles (blue), but also bundles of streamlines along its course that diverged superiorly into the telencephalic wall (arrow).