Table 1.

Neuropathology and extracranial pathologies of investigated fetal subjects.

Subject #	Gestational age at time of fetal MRI (in gestational weeks + days)	Gestational age at time of death	Neuropathology	Extracranial pathologies
Subject 1	20 + 2	21 + 3	No signs of cerebral malformations	Placental hypoplasia, small for gestational age, coarctation of the aorta
Subject 2	20 + 1	22 + 0	Joubert syndrome with hypoplastic vermis and molar-tooth configuration of the mesencephalon, heterotopic projection of the pyramidal tract into the interpeduncular cistern with interpeduncular white matter heterotopia and absence of the pyramidal tract caudal to the mesencephalon, normal anatomy of corpus callosum and internal capsule	Multicystic kidneys
Subject 3	20 + 4	22 + 1	Complete ACC, abnormal gyri and sulci in both frontal lobes, periventricular and subcortical gray matter heterotopia, malrotation of the right hippocampus, disorganized fiber architecture in the left corona radiata	No extracranial malformations
Subject 4	22 + 0	22 + 4	Complete ACC, subependymal heterotopia, hippocampal malrotation, cerebellar hypoplasia	Hypertelorism
Subject 5	22 + 0	23 + 5	Complete ACC, abnormal gyri and sulci in both frontal lobes, malformation of the left frontal lobe with disturbed lamination of the telencephalic wall, abnormal white matter architecture, and enlarged ganglionic eminence, midline cyst	Hypertelorism, epicanthic folds
Subject 6	25 + 1	26 + 3	No signs of cerebral malformations	Congenital muscular dystrophy, pulmonary hypoplasia, cardiac dilatation
Subject 7	27 + 1	29 + 0	Complete ACC, abnormal gyri and sulci in the right frontal lobe, delayed sulcation in the temporal lobes	Parvovirus infection, no extracranial malformations