Table 1. Demographic and cerebral angiographic findings of patients.

No.	Age (yr)	Sex	Eye	Cosmetic Injection			Diagnosis	Skin Necrosis	MRI Brain	Angiographic findings		Time to Visit/IAT	Thrombolysis	Visual acuity baseline/final	Follow-up Period
				Substance	Site	Dose				Ophthalmic Angiogram Obstruction level	ECA Angiogram Distal angiographic runoff
1	24	F	R	HA	Glabella, nose	0.2 mL	OAO	Yes	Normal	2nd branch (Ciliary branch)	Diminished	1 hr/3.5 hr	Hyaluronidase 1,000 units/recanalization fail	NLP/NLP	7 mo
2	34	F	R	HA	Glabella, nose	0.7 mL	OAO	Yes	Normal	Distal to 2nd branch	Diminished	4 hr/5 hr	Hyaluronidase 1,500 units + UK 20,000 units/recanalization fail	NLP/NLP	3 mo
3	39	F	L	HA	Glabella, nose	Unknown	OAO	Yes	Normal	Distal to 2nd branch	Diminished	1 hr/3 hr	Hyaluronidase 9,000 units/partial recanalization	HM/NLP	7 mo
4*	41	F	R	HA	Glabella, nose	0.4 mL	OAO	No	Normal	2nd branch	Preserved	2 hr/4.5 hr	Hyaluronidase 1,600 units/recanalization fail	NLP/NLP	7 day
5	40	F	L	Fat	Nose	Unknown	OAO	No	Normal	OphA before branching	Preserved	1 hr/2.5 hr	UK 500,000 units + tirofiban 500 µg /partial recanalization	NLP/NLP	17 mo
6	66	F	L	Fat	Glabella, nose	Unknown	OAO	No	Normal	OphA before branching	Preserved	2 hr/3 hr	UK 40,000 units/recanalization fail	NLP/NLP	5 day
7	40	F	R	Fat	Glabella	Unknown	CRAO	No	MCA infarct	OphA before branching	Preserved	4 hr/5 hr	UK 40,000 units/recanalization fail	NLP/NLP	5 mo

^*This patient was treated with subcutaneous hyaluronidase injection immediately after the onset of visual symptom by the physician who performed cosmetic filler injection. CRAO, central retinal artery occlusion; ECA, external carotid artery; F, female; IAT, intra-arterial thrombolysis; L, left; HA, hyaluronic acid; HM, hand motion; MCA, middle cerebral artery; MRI, magnetic resonance imaging; NLP, no light perception; OAO, ophthalmic artery occlusion; OphA, Ophthalmic artery; R, right; UK, urokinase.