Table 2. Comparison of the cell migration assay by all NSAIDs eye drop solutions tested.
Exposed time | Eye drop solutions | |||||
---|---|---|---|---|---|---|
Control | Ofenac® | Pranoprofen® | Bronuck® | FML® | ||
1 hr | Acellular Zone (number of pixels) | 5,436 ± 158 | 6,369 ± 129 | 6,457±157 | 5,141 ± 151 | 5,879 ± 140 |
P value | 0.26 | 0.833 | 0.986 | 0.746 | ||
24 hr | Acellular Zone (number of pixels) | 2,682 ± 149 | 4,951 ± 136 | 1,786 ± 104 | 2,188 ± 145 | 4,342 ± 139 |
P value | 0.774 | 0.052 | 0.955 | 0.54 | ||
48 hr | Acellular Zone (number of pixels) | 453 ± 139 | 12,949 ± 144 | 674 ± 136 | 721 ± 111 | 3,427 ± 151 |
P value | < 0.001* | 0.486 | 0.328 | 0.002* |
Acellular zone: values are mean±standard deviation. P value by Mann-Whitney U-test between control and medication group. *Significant value.