Table 1.
Characteristic | Microparticles |
Size | 100-1000 nm |
Mechanism of formation | Outward blebbing of plasma membrane |
How detected | Flow cytometry, capture-based assays and electron microscopy |
Characteristic features | Annexin V-positivity and presence of cell-specific surface markers |
Composition | Protein, RNA and miRNA |
Membrane properties | Externalized phosphatidylserine, rich in lipid rafts and impermeable |
Name of antigens | CD31 (PECAM-1) |
CD51 (vitronectin receptor, αv β3) | |
CD105 (endoglin) | |
CD144 (VE-cadherin) | |
CD146 (S-Endo 1-associated antigen) |