Table 1.
Patient demographics
| Known prior change of IS (n = 4) | No known prior change of IS (n = 3) | All cases (n = 7) | |
| Age, years (range) | 55.5 (43-68) | 38.7 (15-58) | 48.3 (15-68) |
| Sex, n | |||
| Male | 4 | 3 | 7 |
| Female | 0 | 0 | 0 |
| Cause of end stage renal disease, n | |||
| DM ± HTN | 4 | 1 | 5 |
| PCKD | 0 | 1 | 1 |
| CON | 0 | 1 | 1 |
| No. of HLA matches, average (range) | |||
| Class I (HLA-A, HLA-B) | 0.25 (0-1) | 0 | 0.14 (0-1) |
| Class II (HLA-DR) | 0.50 (0-2) | 0.33 (0-1) | 0.43 (0-2) |
| Donor age, years (range) | 38.5 (17-57) | 22.0 (18-30) | 31.4 (17-57) |
| Cold ischemia time, hours (range) | 22.4 (15.0-37.5) | 17.8 (14.1-21.2) | 20.4 (14.1-37.5) |
| Delayed graft function, n | 1 | 0 | 1 |
| Baseline creatinine, mg/dL (range) | 1.4 (1.1-1.8) | 1.6 (1.2-1.8) | 1.4 (1.1-1.8) |
| Time of index biopsy, months after | 231 (135-317) | 507 (45-1293) | 349 (45-1293) |
| transplant (range) | |||
| Creatinine at index biopsy, mg/dL | 3.3 (1.8-6.2) | 1.9 (1.7-2.2) | 2.7 (1.7-6.2) |
| (range) | |||
| Donor-specific antibodies prior to | 0 | 0 | 0 |
| transplant |
HLA: Human leukocyte antigen; DM: Diabetes mellitus; HTN: Hypertension; PCKD: Polycystic kidney disease; CON: Congenital obstructive nephropathy; IS: Immunosuppression.