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. 2015 Oct 7;44(6):1833–1841. doi: 10.1093/ije/dyv176
n = 3427 Data set 1
Matched birth records for cohort members born as singletons in HMH, Mysore between 1934 and 1966.

  • Contemporaneous data from birth records:

  • Paternal : occupation and religion.

  • Maternal : age, weight (40%), years of marriage, parity, religion and pelvic measurements (55%) (interspinal, intercristal and external conjugate diameters).

  • Antenatal : 40% of the records have date of last menstrual period, haemoglobin and blood pressure at antenatal visits.

  • Obstetric history including birth order.

  • Labour data : Maternal pulse and blood pressure; urine: specific gravity, sugar and albumin; course of labour, drugs administered and mode of delivery (normal, forceps or caesarean).

  • Child : gender, birthweight, birth length and head circumference at birth.

  • Placenta : insertion of cord, length of cord and cord condition.

  • Postpartum : the day after delivery.

n = 1069 Data set 2
First study of the cohort between 1993 and 2003. The participants were then aged between 40 and 60 years.
  1. Blood tests:
    1. Biochemistry: glucose tolerance test (WHO protocol, with blood taken fasting and 30 and 120 min after a 75-g glucose load), plasma insulin (fasting, 30 and 120 min post glucose), fibrinogen, factor VII, total cholesterol, triglycerides, LDL and HDL cholesterol, serum cortisol and cortisol-binding globulin ( n  = 509).
    2. Haematology: full blood count, differential cell count, haemoglobin.

  2. Anthropometry : height, weight, head circumference, hip and waist circumferences and skin-fold thicknesses (triceps, biceps, subscapular, supra-iliac).

  3. DNA ( n  = 551).

  4. Clinical evaluation : pulse rate, blood pressure, electrocardiographs (Minnesota coded), Rose angina questionnaire and spirometry ( n  = 518).

  5. Structured Interview:
    1. Marital status, family structure and living arrangements.
    2. Medication, medical history of stroke, angina, hypertension, diabetes, chronic bronchitis and emphysema, history of coronary artery bypass graft or angioplasty.
    3. Family history of coronary heart disease and diabetes. d. Physical activity at home and at work
    4. Alcohol and tobacco consumption f. Dietary history: vegetarian/non-vegetarian, dietary intake of meat, dairy products, fish, fruits, vegetables and oils per week.

  6. Kuppuswamy scale for socioeconomic indicators: 35 locality in the town, household amenities (water, bathroom, toilet facilities), education level of subject and spouse, income of subject and spouse, occupation of subject and spouse, number of members in the household and number per room, total family income and per capita income.

  7. Collected as a part of the tracing process : birth order, family size, maternal and paternal occupation.

After the initial study, a subset of the 1069 participated in follow-up studies; for these, in addition, to data set 1 and data set 2, the following additional data sets are available
n = 435 Data set 3
Of the 1069, 435 examined between 1993 and 1995 participated in a follow-up study to examine cardiac dimensions and arterial compliance in 1996 –97. The participants were then aged between 43 and 63 years.

  1. Blood pressure, weight, height.

  2. Cardiac dimensions, pulse wave velocity, arterial compliance, left ventricular mass.

  3. Electrocardiograph.

  4. Hand Xray and osteoarthritis questionnaire.

  5. Reproductive history for women only (age of menarche, parity, pregnancies and breastfeeding).

  6. Medications
n = 383 Data set 4
Of the 1069, 383 examined between 1993 and 1995 were followed up 10 years later between 2003 and 2004, to study incident diabetes. The participants were then aged between 50 and 70 years.
  1. Blood tests:
    1. Biochemistry: glucose tolerance test, plasma insulin (fasting, 30 and 120 min post glucose), fibrinogen, factor 7, total cholesterol, triglycerides, LDL and HDL cholesterol.
    2. Haematology: full blood count, differential cell count, haemoglobin.

  2. Anthropometry : height, weight, hip and waist circumferences and skin-fold thicknesses.

  3. Clinical evaluation : pulse rate, blood pressure, electrocardiography, spirometry, Rose angina questionnaire.

  4. Structured Interview:
    1. Marital status, family structure and living arrangements.
    2. Medications, medical history for stroke, angina, hypertension, diabetes, chronic bronchitis and emphysema, history of coronary artery bypass graft or angioplasty.
    3. Family history of CHD and diabetes.
    4. Physical activity at home and at work.
    5. Alcohol and tobacco consumption.
    6. Diet and food frequency schedule: vegetarian/non-vegetarian, dietary intake of meat, dairy products, fish, fruits, vegetables and oils per week.

  5. Kuppuswamy scale for socioeconomic indicators: 35 locality in the town, household amenities (water, bathroom and toilet facilities), education levels of subject and spouse, income of subject and spouse, occupation of subject and spouse, number of members in the household and number per room, total family income and per capita income.

  6. Bio impedance recordings : total body fat weight, lean weight, body water and metabolic rate.

  7. Medical history for peptic ulcer disease and H. Pylori infection and any surgical procedures.