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. 2015 Oct 14;6(4):977–990. doi: 10.3390/genes6040977

Table 2.

Log-rank analysis for individual variables (covariates) and multiple Cox-regression analysis of all the included variables.

Covariate Log-Rank Analysis Multiple Cox Regression Analysis
Coefficient HR 95% CI p-value Coefficient HR 95% CI p-value
Age (≥65 years) 1.286 3.617 1.305–10.030 0.008 1.506 4.508 1.373–14.801 0.013
Sex −0.002 0.998 0.578–1.723 0.995 −0.268 0.765 0.416–1.405 0.388
VTRNA1-3 methylation 0.562 1.755 1.031–2.985 0.037 0.360 1.434 0.801–2.566 0.225
IPSS score (0 vs. 0.5–1) 0.369 1.446 0.843–2.479 0.178 0.022 1.022 0.510–2.046 0.951
Blast count
(<5% vs. 5%–10%)
1.098 2.999 1.397–6.437 0.003 1.310 3.705 1.574–8.722 0.003
Cytogenetics (good vs. intermediate/poor) 0.854 2.350 1.236–4.465 0.007 1.195 3.303 1.662–6.564 0.001