Table 1.

Possible translational applications of brief gluten challenge.

Application	Clinical/Research Purpose	References
Diagnosis	Confirmation of diagnosis in uncertain celiac disease cases	[10,67]
Therapies	Validation of new therapeutic drugs	[62]
Therapies	Validation of biochemical or enzymatic strategies to detoxify gluten.	[64,65]
Therapies	Searching of wheat cultivars with reduced immunotoxic gluten sequences	[68]
Pathogenesis	Identification of immunogenic gluten epitopes	[32,60]
Pathogenesis	Phenotypic analysis of cell population involved in celiac disease	[53]