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Working principle of the DNA hydrogel encapsulating AuNPs for visual detection of Ochratoxin A (OTA). The formation of OTA-aptamer complex collapses the backbone of the hydrogel network and the preloaded AuNPs in the hydrogel are released, leading to a change of the supernatant from colorless to red, which could be observed by the naked eye (Adapted from Ref. [80], Copyright 2015, American Chemical Society).
