Table 8.
Clinical factors that affect dropout n (%)
| Total | Drop |
Univariate |
Multivariable1 |
|||
| OR (95%CI) | P value | OR (95%CI) | P value | |||
| Sex | < 0.001 | < 0.001 | ||||
| Male | 2920 | 534 (18.29) | 1.622 (1.372-1.917) | 1.459 (1.228 -1.734) | ||
| Female | 1880 | 228 (12.13) | 1 | 1 | ||
| Age (yr) | ||||||
| ≤ 65 | 3562 | 462 (12.97) | 1 | 1 | ||
| > 65 | 1238 | 300 (24.23) | 2.146 (1.824 -2.525) | < 0.001 | 1.727 (1.448-2.059) | < 0.001 |
| BMI (kg/m2) | ||||||
| ≤ 25 | 3325 | 496 (14.92) | 1 | |||
| > 25 | 1475 | 266 (18.03) | 1.255 (1.066-1.478) | 0.006 | ||
| Anastomosis method | ||||||
| Intra | 2345 | 378 (16.12) | 1 | 1 | ||
| Extra | 2455 | 384 (15.64) | 0.965 (0.826-1.126) | 0.651 | 1.057 (0.900-1.242) | 0.499 |
| Resection | ||||||
| Distal | 4218 | 593 (14.06) | 1 | 1 | ||
| Total | 582 | 169 (29.04) | 2.501 (2.050-3.052) | < 0.001 | 2.444 (1.988-3.005) | < 0.001 |
| Resection group | ||||||
| I-distal | 2018 | 285 (14.12) | 1 | < 0.001 | ||
| I-total | 327 | 93 (28.44) | 2.417 (1.843 -3.169) | < 0.001 | ||
| E-distal | 2200 | 308 (14.00) | 0.990 (0.832 -1.178) | 0.909 | ||
| E-total | 255 | 76 (29.80) | 2.582 (1.920-3.472) | < 0.001 | ||
| Combined OP | ||||||
| None | 4531 | 694 (15.32) | 1 | 1 | ||
| Yes | 269 | 68 (25.28) | 1.870 (1.404-2.491) | < 0.001 | 1.731 (1.284-2.334) | < 0.001 |
| OP event | ||||||
| None | 4723 | 732 (15.50) | 1 | 1 | ||
| Yes | 77 | 30 (38.96) | 3.480 (2.187-5.539) | < 0.001 | 2.558 (1.554-4.212) | < 0.001 |
| Number of comorbidities | ||||||
| 0 | 3196 | 411 (12.86) | 1 | < 0.001 | 1 | 0.031 |
| 1 | 1137 | 221 (19.44) | 1.635 (1.366 -1.957) | < 0.001 | 1.179 (0.882 -1.576) | 0.266 |
| 2 and more | 467 | 130 (27.84) | 2.614 (2.082-3.281) | < 0.001 | 1.564 (1.110-2.204) | 0.011 |
| ASA score | ||||||
| 1 | 3025 | 382 (12.63) | 1 | < 0.001 | 1 | 0.006 |
| 2 | 1549 | 305 (19.69) | 1.696 (1.438-2.000) | < 0.001 | 1.182 (0.893-1.565) | 0.242 |
| 3 | 226 | 75 (33.19) | 3.437 (2.554-4.625) | < 0.001 | 1.889 (1.271-2.808) | 0.002 |
| Abdominal OP history | ||||||
| None | 4057 | 661 (16.29) | 1 | |||
| Yes | 743 | 101 (13.59) | 0.808 (0.645-1.013) | 0.065 | ||
| TNM stage | ||||||
| I | 4380 | 688 (15.71) | 1 | 0.274 | ||
| II | 314 | 51 (16.24) | 1.041 (0.763-1.420) | 0.802 | ||
| III | 106 | 23 (21.70) | 1.487 (0.930-2.377) | 0.097 | ||
1
Backward elimination. Logistic regression to predict dropout (= 762/4800). OR: Odd ratio; BMI: Body mass index; Intra/I: Intracorporeal anastomosis; Extra/E: Extracorporeal anastomosis; OP: Operation; ASA: American Society of Anesthesiologists.