Table 2.
Turnaround time and reagent costs to detect Clostridium difficile infection in the laboratory
| Stool extraction | Labor time (min) | Turnaround time of test (min) | Apparatus | Individual or series test | Algorithm cost ratio relative to DiaSorin algorithm (%) | ||
|---|---|---|---|---|---|---|---|
| DiaSorin | GDH | Yes | 15 | 45 | Liaison random access | Both | 100 |
| Toxins A and B | Yesa | 0a | 45 | Liaison random access | Both | ||
| Meridian | ImmunoCard® GDH | No | 5 | 30 | No | Individual | 90 |
| illumigene ® | No | 15 | 45 | illumipro® | Individual | ||
| Alere | C. DIFF Quik Chek GDH® | No | 5 | 30 | No | Individual | 50 |
| TOX A/B Quik Chek® | No | 5 | 30 | No | Individual |
The cost of each algorithm was evaluated in comparison to the DiaSorin algorithm whose the global costs represent 100 %
aThe DiaSorin LIAISON® apparatus is configured in order to automatically perform the toxin assay in case of a positive GDH result (reflex testing). These two assays were performed on the same stool extract