Table 3.
Optimal cut-offs of liver and spleen stiffness for prediction of clinically significant (≥10 mmHg) and severe (≥12 mmHg) portal hypertension
| HVPG | Method | Cut-off, kPa | Sensitivity, % | Specificity, % | PPV, % | NPV, % | Accuracy, % |
|---|---|---|---|---|---|---|---|
| ≥10 mmHg | Liver TE | 17.4 | 88.0 | 87.5 | 95.8 | 74.2 | 88.7 |
| Spleen TE | 47.6 | 77.3 | 79.2 | 92.0 | 52.7 | 77.7 | |
| ≥12 mmHg | Liver TE | 20.6 | 82.8 | 80.0 | 88.8 | 0.75 | 83.1 |
| Spleen TE | 50.7 | 78.1 | 77.1 | 86.2 | 65.8 | 77.7 |
HVPG hepatic venous pressure gradient, PPV positive predictive value, NPV negative predictive value