Table 3.
Spearman’s rank correlation coefficients between ISG15, PKR, OAS1, Mx1, and Mx2 protein levels with their gene expression as well as TMEV RNA, inflammation, T cells, B cells, microglia/macrophages, and demyelination in the spinal cord of SJL/J mice
| ISG protein | ISG mRNA | TMEV RNA | Inflammation (HE) | T cells (CD3) | B cells (CD45R) | Microglia/ Macrophage (MAC3) | Demyelination (LFB) |
|---|---|---|---|---|---|---|---|
| ISG15 | 0.499 | 0.528 | 0.484 | 0.445 | 0.363 | 0.580 | 0.316 |
| PKR | 0.497 | 0.417 | 0.480 | 0.444 | 0.371 | 0.434 | 0.445 |
| OAS1 | 0.208 | 0.118 | 0.316 | 0.192 | 0.163 | 0.393 | 0.212 |
| Mx1 | 0.566 | 0.566 | 0.296 | 0.604 | 0.675 | 0.659 | 0.546 |
| Mx2 | 0.380 | 0.537 | 0.356 | 0.509 | 0.465 | 0.479 | 0.505 |
Significant correlations are marked in italics (P ≤ 0.05)