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. 2015 Dec 24;3:22. doi: 10.1186/s40349-015-0044-5

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© Magnin et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Trajectory drawing and application to hemispheric and global permeabilization. a (resp. d and f) Trajectories which were designed in the control software for hemispheric BBB disruption in rats (resp. global BBB permeabilization in rats and hemispheric BBB disruption in mice). c (resp. g) Axial T₁-weighted image obtained after Gd chelate injection, showing contrast enhancement only in the hemisphere which has been disrupted in rat (resp. mice). b The corresponding T₁-weighted image obtained in the same rat in horizontal orientation. e T₁-weighted image obtained in horizontal orientation for the rat with global BBB permeabilization