Table 2.
Independent prognostic factors associated with time to death at multivariate analysis using cox proportional hazards model
| HR | 95 % CI | P value | |
|---|---|---|---|
| Age | 0.000 | ||
| <60 | Ref | - | |
| ≥60 | 1.760 | 1.489–2.079 | |
| ECOG PS | 0.001 | ||
| 0–1 | Ref | - | |
| 2–5 | 1.968 | 1.317–2.940 | |
| Tumor size | 0.014 | ||
| <5 cm | Ref | ||
| ≥5 cm | 1.267 | 1.050–1.529 | |
| Depth | 0.000 | ||
| T1 | Ref | - | |
| T2 | 1.499 | 1.097–2.050 | |
| T3 | 2.160 | 1.640–2.845 | |
| T4a | 3.153 | 2.338–4.253 | |
| T4b | 4.910 | 2.504–9.628 | |
| Nodal status | 0.000 | ||
| N0 | Ref | - | |
| N1 | 1.151 | 0.820–1.616 | |
| N2 | 1.379 | 0.979–1.942 | |
| N3 | 2.863 | 2.062–3.976 | |
| TNM Stage | 0.000 | ||
| I | Ref | - | |
| II | 2.328 | 1.752–3.093 | |
| III | 3.387 | 2.235–5.133 |
HR Hazard ratio, CI Confidence interval, ECOG Eastern cooperative oncology group, PS Performance status, TNM Tumor-node-metastasis