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. 2015 Dec 10;3:e1489. doi: 10.7717/peerj.1489

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© 2015 Raavé et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

PMC Copyright notice

PubMed and EMBASE via OvidSP were searched using developed search strings to identify studies that used chemotherapeutics in a DDS in ovarian cancer animal models. All studies were first screened by title and abstract according to predefined inclusion and exclusion criteria. Subsequently studies were more specifically assessed by full text. Screenings were performed by two reviewers (RR and WD). Full text studies excluded for “others” were: (1) no full text was available or only an abstract that did not include sufficient information (n = 12); (2) conference abstract of a previously assessed full-text study (n = 5); (3) the study included only a biodistribution experiment (n = 4).