. Author manuscript; available in PMC: 2015 Dec 24.

Published in final edited form as: Curr Opin Clin Nutr Metab Care. 2011 Jul;14(4):341–346. doi: 10.1097/MCO.0b013e328347970b

Table 2.

Adipose tissue macrophage subtypes in mice

	Type 1a ATMs	Type 1b ATMs	Type 2 ATMs	Type 3 ATMs
Surface markers	CD11c⁺CD206⁻MGL1⁻	CD11c⁺CD206⁺ MGL1^mid	CD11c⁻CD206⁺MGL1^hi	CD11c⁻CD206⁻
Change with obesity	↑	↑	↓ or =	↑
Gene expression	Tnfα, Il6, Nos2, Ccr7	Il12, Arg1	Arg1, Mgl1/2, Il10, Ccl8, Cx3cl1, Ccl2	Arg1, Chi3l3, Ccr2, Cx3cr1, Ccr1, Ccr9
Localization	CLS	CLS	Interstitial	CLS
Recruitment kinetics in obesity	Fast	n.d.	Slow	n.d.
Lipid content	High	High	Low	n.d.
References	[11^•,12^•,13,24^•]	[12^•,24^•]	[11^•,12^•,13,24^•]	[11^•]

ATMs, adipose tissue macrophages; CLS, crown-like structures; n.d., no data; ↑, increased; ↓, decreased; =, unchanged.