Table 1.
67 Families | Additional 215 Families | |
---|---|---|
Families, n | 67 | 215 |
Subjects, n | 469 | 591 |
Affection status, n (%) | ||
Affected | 354 (75.5) | 434(73.4) |
Average (SD) of affected individuals per family | 5.1 (1.8) | 2.1 (0.8) |
Unaffected | 114 (24.3) | 156(26.4) |
Average (SD) of unaffected individuals per family | 2.2 (1.5) | 1.5 (0.9) |
Unknown | 1 (0.2) | 1(0.2) |
Females, n(%) | 276 (5.9) | 385(65.1) |
Age at onset of affecteds, mean (SD) | 74 (9.6) | 74.1(9.5) |
Age at last examination of unaffecteds, mean (SD) | 68 (9.7) | 69.6(8.3) |
APOE allele frequency, n (%) | ||
ε4 | 165 (17.6) | 309(26.1) |
ε3 | 735 (78.4) | 821(69.5) |
ε2 | 38 (4.0) | 52(4.4) |