Table 2.

Risk factor distribution in the HCC cohort by cirrhosis category (N=1395)^*. Risk factor distribution is not mutually exclusive as many patients had more than 1 risk factor.

Risk factor n (%)	Level 1 evidence of no cirrhosis n= 43	Level 2 evidence of no cirrhosis n= 151	Confirmed Cirrhosis n=1201	P value
NAFLD	6 (5.6)	31 (28.9)	70 (65.4)	<0.01
HCV	18 (1.9)	67 (7.0)	867 (91.1)	<0.01
HBV	2 (3.1)	3 (4.6)	60 (92.3)	0.25
Alcohol abuse	29 (2.6)	96 (8.5)	1008 (88.9)	<0.01
Metabolic syndrome	14 (3.9)	54 (15.1)	289 (80.9)	<0.01
Others**	2 (8.0)	3 (12.0)	20 (80.0)	0.45
Idiopathic***	2 (5.9)	11 (32.4)	21 (61.8)	<0.01

HCV-hepatitis C virus; HBV-hepatitis B virus; NAFLD-nonalcoholic fatty liver disease

^*Of 1500, 105 had insufficient information to classify in any cirrhosis category

^**Others – Hemochromatosis, autoimmune hepatitis, alpha-1 antitrypsin deficiency

^***None of the above