. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Arthritis Rheumatol. 2016 Jan;68(1):92–102. doi: 10.1002/art.39419

Table 3.

Multivariable Associations of PBMC Subsets with the Outcome of Presence of Any CAC^***

	Crude Models		Adjusted Models^*		Extended Model^**		Reduced Model
	OR	p	OR	p	OR	p	OR	p
% CD4 CD8 (in CD3⁺)	0.90	0.25	0.97	0.76
log % CD28 (in CD4⁺)	1.45	0.033	1.15	0.52
square root % CD57 (in CD4 )	1.58	0.015	1.30	0.25
square root% CD57⁺ (in CD4+ CD56⁺)	1.48	0.003	1.31	0.083	1.27	0.23	1.40	0.046
square root % CD28 CD57+ (in CD4⁺)	1.40	0.032	1.19	0.35
square root % HLA-DR⁺ (in CD4⁺⁾	3.49	0.003	2.33	0.090	1.22	0.80
square root % HLA-DR⁺ CD28 (in CD4+)⁺	2.25	0.018	1.50	0.31
log % CD28− (in CD8+)	3.08	0.010	1.90	0.23
% CD57+ (in CD8+)	1.76	0.002	1.37	0.17
%CD8⁺ CD56⁺that are CD57⁺	1.04	0.002	1.03	0.091	1.01	0.61
% CD57+ in CD8+ CD56+)	1.05	0.008	1.02	0.31
log % CD57+ in CD8+ CD56+)	2.38	0.014	1.58	0.31
square root % HLA-DR+ (in CD8+)	1.84	0.006	1.53	0.11	1.12	0.79
square root% HLA-DR+ CD28− (in CD8+)	1.43	0.055	1.41	0.19
%CD14^hi CD16⁺	1.10	0.066	1.16	0.001	1.17	0.045	1.19	0.027
%CD16⁺	1.07	0.035	1.12	0.023
%CD14^hi CD16	0.95	0.079	0.96	0.25
square root all %CD3⁺ CD57⁺	1.68	0.001	1.34	0.14
log all %CD3 CD28	3.01	0.008	1.86	0.21
square root all %CD3⁺ HLA-DR⁺	1.89	0.003	1.56	0.081

Adjusted Models are three covariate models containing the PBMC variable of interest, age, and SBP

^**

The Extended Model contains all 5 PBMC variables listed in the same model, plus age and SBP

^***

Abbreviations: PBMC Peripheral Blood Mononuclear Cells, CAC Coronary Artery Calcification.