Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 26;16(12):28108–28122. doi: 10.3390/ijms161225997

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

SPARC expression during ductal breast carcinoma progression from dysplasia until bone metastasis for Patient 3. Representative images of immunohistochemical staining for SPARC were shown. In bone metastasis established in the mandible, TRAP assay was also performed. Magnifications of details are shown. ECM, Extracellular matrix; me, metastatic cells; m-oc, mature osteoclasts. Negative controls were assayed without the specific antibody. The histograms, showing the relative values for SPARC expression, were prepared by using the score values reported in Supplementary Table S1. The data are the means ± S.E. of experiments performed in triplicate.